From the September 18, 2009 NASA Press Release:

NASA has assigned the crew for the last scheduled space shuttle mission, targeted to launch in September 2010.The flight to the International Space Station will carry a pressurized logistics module to the station.

Veteran shuttle commander and retired Air Force Col. Steven W. Lindsey will command the eight-day mission, designated STS-133. Lindsey earned a M.S. in Aeronautical Engineering from AFIT in 1990.

Lindsey will be making his fifth shuttle flight. He served as the pilot of STS-87 in 1997 and STS-95 in 1998, and commanded STS-104 in 2001 and STS-121 in 2006.